free thyroxine index vs free t4

Use the serum free-T4 L-thyroxine level to monitor adequacy of therapy in this patient population. Moreover in athyreotic individuals treated with LT 4 to achieve a normal serum TSH the serum FT 4 is usually higher and the serum T 3 is either normal 38 39 or lower than the values seen.

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Thyroid hormone replacement therapy with oral levothyroxine LT4 is the standard treatment for patients with hypothyroidism 13The goals of treatment include resolution of symptoms and signs of hypothyroidism and normalization of circulating thyroid-stimulating hormone TSH levels Orally administered LT4 is available in several formulations.

. With such therapy there will be a transient peak in serum T 4 and free FT 4 levels of about 15 magnitude about 4 hours after LT 4 administration. Pediatric Dosage - Congenital Or Acquired Hypothyroidism. The increase in kidney clearance during pregnancy causes more iodide to be excreted and causes relative iodine deficiency and as a result an increase in thyroid size.

Titrate EUTHYROX dosing per above instructions until the patient is clinically euthyroid and the serum free-T4 level is restored to the upper half of the normal range. Estrogen-stimulated increase in thyroid-binding globulin TBG leads to an increase in total thyroxine T4 but free thyroxine T4 and triiodothyronine T3 remain normal.

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